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Mar 29, 2026

a department of MediStem Panama. The sponsor had the responsibility of initiating

managing

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Mar 29, 2026

the trends observed in this study are indicative of potential therapeutic benefits

reflected in lower CARS and ATEC scores that may be associated with decreases in TARC and MDC levels.

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Mar 29, 2026

which impacted the statistical power of the analyses. Although a sample size of 20 subjects was still within FDA guidelines for phase I clinical trials

measurements at all time points were not completed by all participants

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Mar 29, 2026

and MSCs have anti‐inflammatory and immune‐regulating properties that made them an interesting option to treat ASD symptoms. With this study

we have established that repeated infusions with UC MSCs are safe

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Mar 29, 2026

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Mar 29, 2026

preclinical studies have reported that repeated doses of MSCs are more beneficial than a single dose for the treatment of other conditions49-51. Repeated dosage has consequently been proposed as a new paradigm in stem cell therapy52

53 and has been applied for other medical conditions15

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