The paradoxical role of lipid peroxidation on carcinogenesis and tumor growth: a commentary.The paradoxical role of lipid peroxidation on carcinogenesis and tumor growth: a commentary.
González MJ, Riordan NH.
Med Hypotheses. 1996 Jun;46(6):503-4
Lipid peroxidation has been shown to both enhance carcinogenesis and to have an anticarcinogenic effect. This paradox is of great relevance to the fields of free radical biology, biochemistry, pathology, nutrition and oncology among others and needs to be addressed. A proper understanding of this issue can be a key to more effective treatment of malignant tumors in the near future.
6/1/1996
Med Hypotheses. 1996 Jun;46(6):503-4
González MJ, Riordan NH.
Lipid peroxidation has been shown to both enhance carcinogenesis and to have an anticarcinogenic effect. This paradox is of great relevance to the fields of free radical biology, biochemistry, pathology, nutrition and oncology among others and needs to be addressed. A proper understanding of this issue can be a key to more effective treatment of malignant tumors in the near future.
https://www.sciencedirect.com/science/article/abs/pii/S0306987796901206
Anticarcinogenic Agents; Antioxidants; Cell Death; Cell Transformation; Neoplastic*; Free Radicals / Metabolism; Humans; Lipid Peroxidation*; Models; Biological*; Neoplasms / Genetics; Neoplasms / Pathology; Neoplasms / Physiopathology*; Neoplasms / Prevention & Control